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KMID : 0878220060180030131
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Journal of Sasang Constitutional Medicine
2006 Volume.18 No. 3 p.131 ~ p.144
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A Study on Sasang Constitutional Gene Selection Using DNA Chips by Multivariate Analysis
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Kim Pan-Joon
Seo Eun-Hee
Lee Jung-Hwan
Ha Jin-Ho
Choi Hong-Sik
Jung Tae-Young
Goo Deok-Mo
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Abstract
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1. Objectives
This research uses the DNA chip, which includes 16,383 gene code, and various statistic prediction way that shows objectification index for the objectification of constitution diagnosis.
2. Methods
Drawing blood whose constitution is confirmed, and analyze its gene information by using 1.7k DNA chip to find the gene correlation through multivariate statistical method.
3. Results and Conclusions
Distinctive genes such as AK001919, U09384, NM_001805, X99962, NM_004796, AK026738, AL050148, BC002538, AK027074, AK026219, AF087962, AL390142, NM_015372, AL157466, NM_002446, AK024523, NM_014706, NM_014746 and AL137544 were related to Taeumin; AL157448, NM_005957, NM_005656, NM_017548, AK027246, NM_003025, NM_012302 and NM_005905 were represented in Soeumin, while AK026503, AF147325, NM_002076, AF147307, AK001375, NM_003740, NM_005114, AB007890, NM_005505, NM_015900, NM_014936, Z70694, AB023154, U52076, NM_004360, NM_005835, NM_017528, AF087987, NM_014897, AK021720, NM_006420, AJ277915, AK002118 and AK021918 were for Soyangin. This study figured out the possibility to develop the prediction system by sorting each constitution’s gene, and research each constitution’s distinctive character of manifestation pattern.
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KEYWORD
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Sasang Constitution, Gene, DNA Chip, Multivariate Statistical Method
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